Faculty Title:
Assistant Professor of Biological Engineering
Department:
- Biological Engineering (BE)
Room:
56-787b
Phone Number:
617-253-6086
Email:
Research Areas:
- Bioengineering and Neuroengineering
- Cancer Systems Biology
- Cellular Biophysics
- Evolutionary and Computational Biology
- Molecular Biophysics and Structural Biology
- Quantitative Imaging
- Regulatory Genomics, Epigenomics, and Proteomics
- Single Cell Manipulations and Measurement
- Stem Cell and Developmental Systems Biology
- Synthetic Biology and Biological Design
Research Summary:
We are interested in understanding how genome structure relates to function. Towards this, we develop new super resolution microscopy approaches to follow chromatin looping, enhancer-promoter communication, and transcription in living cells with single molecule resolution. We are particularly interested in understanding how 3D genome architecture regulates gene expression during development, and how dysregulation of genome topology can cause disease.