Using this new approach, researchers could develop drug compounds with unique pharmaceutical properties.
Researchers from MIT and the University of Michigan have discovered a new way to drive chemical reactions that could generate a wide variety of compounds with desirable pharmaceutical properties.
These compounds, known as azetidines, are characterized by...
CSB PhD Candidate: Sameed Siddiqui
Faculty Advisors: Prof. Pardis Sabeti & Prof. James Collins
Date: Friday, June 7, 2024
Time: 2:00 PM EST
Room: 68-181
Thesis title: Serology, CRISPR Diagnostics, and Machine Learning Architectures for Biological Sequences
Abstract: Fueled by technological breakthroughs, advancements in our understanding of infectious agents offer unprecedented potential for their early detection, intervention, and ultimately, eradication. This dissertation focuses on combining cutting-edge immunological, diagnostic, and computational approaches to confront infectious diseases more effectively, with a particular emphasis on SARS-CoV-2. The first two chapters delve into the immunological aspects of SARS-CoV-2, exploring the dynamics of antibody responses during primary infection and...
CSB PhD Candidate: Cameron Flower
Faculty Advisor: Prof. Forest White
Date: Friday April 26, 2024
Time: 1:00 PM EST
Thesis title: Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition
Abstract:
Therapeutics targeting oncogenic kinases have offered longer survival and superior quality of life for cancer patients with particular malignancies compared to the preceding standard of care. However, many patients still fail to show a clinically meaningful response to kinase inhibitors prescribed on the basis of tumor genotype, and nearly all responsive patients eventually develop resistance, limiting the curative potential of these agents. A more complete understanding of the molecular basis underlying therapy failure is required for designing new agents and combinations with improved...
L. Chitayat| Photo: Zeno Fox
Age: 20 >> PhD student at MIT
Even before she turned 20, Liyam Chitayat began her doctorate at MIT, one of the leading academic research institutions in the US and the world, and won the Hertz Award for Research Excellence - the most...