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Event

CSB Thesis Defense Miriam Shiffman (Broderick & Regev Labs)

Posted
January 11, 2024

CSB PhD Candidate: Miriam Shiffman

Faculty Advisor: Tamara Broderick & Aviv Regev

Committee members:  Stefanie Jegelka, Allon Klein, Ashia Wilson

Date: Tuesday January 16, 2024

Time: 12:00 PM EST

Thesis title: Uncertainty & robustness for single-cell studies: Could dropping a few cells change the takeaways from differential expression?

Abstract: The advent of new technologies capable of measuring molecular profiles at single-cell granularity, across thousands or millions of cells, offers unprecedented insight into the form, function, and circuitry of biological systems. At the same time, these technologies present particular statistical and computational challenges, including noise, sparsity, technical and biological variability, and multilevel sampling regimes. To distill relevant signal...

Event

CSB Thesis Defense Kayla McCue (Burge Lab)

Posted
January 11, 2024

CSB PhD Candidate: Kayla McCue

Research Advisor: Prof. Chris Burge

Date:  Tuesday, December 19, 2023

Time: 9:00 -10:00 AM

Room: 68-121

Title: Interpretable Computational Modeling of pre-mRNA Splicing for Multiple Eukaryotic Species

Abstract: One of the key steps in eukaryotic gene expression is pre-mRNA splicing, whereby intronic sequences are excised from immature pre-mRNA transcripts, and the remaining exonic sequences are joined together. This process is catalyzed by the spliceosome, a large complex of proteins and RNAs. A variety of RNA sequence features influence this process, including the core splice site (SS) motifs and splicing regulatory elements (SREs), which recruit protein splicing factors. Together these RNA elements and factors form an intricately interconnected regulatory system which is still incompletely...

Event

MIT Computational & Systems Biology PhD Program Webinar

Posted
November 14, 2023

The MIT Computational and Systems Biology Program will hold a webinar on Friday November 17, 2023 from 1:30-2:30 EST.

Please join us to learn about the program, how to apply, and ask any questions you might have.

We look forward to meeting you!

Event

2023 MIT Virtual Graduate Fair

Posted
October 30, 2023

The MIT CSB Program will be participating in the 2023 MIT Virtual Graduate Fair on November 15th from 12:00 -2:00 PM EST!

Register and join us to learn more about the program and receive answers to your questions about applying to the program!

We look forward to meeting you!