CSB PhD Candidate: Miriam Shiffman
Faculty Advisor: Tamara Broderick & Aviv Regev
Committee members: Stefanie Jegelka, Allon Klein, Ashia Wilson
Date: Tuesday January 16, 2024
Time: 12:00 PM EST
Thesis title: Uncertainty & robustness for single-cell studies: Could dropping a few cells change the takeaways from differential expression?
Abstract: The advent of new technologies capable of measuring molecular profiles at single-cell granularity, across thousands or millions of cells, offers unprecedented insight into the form, function, and circuitry of biological systems. At the same time, these technologies present particular statistical and computational challenges, including noise, sparsity, technical and biological variability, and multilevel sampling regimes. To distill relevant signal...