A new analysis reveals how Staphylococcus aureus gains mutations that allow it to colonize eczema patches.
Cancer Systems Biology
Illustration Credit: Jose-Luis Olivares/MIT
Image Credit: Manalis, Lauffenburger, and Shalek labs
Research in Cancer Systems Biology at MIT emphasizes mechanistic understanding of oncogenesis and cancer progression through integration of large-scale –omic data, and single cell analysis
Katie Galloway
A “door” into the mitochondrial membrane
Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria.
New model helps identify mutations that drive cancer
Image: Dylan Burnette and Jennifer Lippincott-Schwartz, National Institutes of Health, edited by MIT News
The system rapidly scans the genome of cancer cells, could help researchers find targets for new drugs.
Francisco J. Sánchez-Rivera
Anders Sejr Hansen
Ifrah Tariq
Anders Sejr Hansen
The fluid that feeds tumor cells
The substance that bathes tumors in the body is quite different from the medium used to grow cancer cells in the lab, biologists report.
Computer model offers more control over protein design
New approach generates a wider variety of protein sequences optimized to bind to drug targets.
Designing synthetic proteins that can act as drugs for cancer or other diseases can be a tedious process: It generally involves creating a library of millions of proteins, then screening the library to find proteins that bind the correct target.
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