Doctoral Thesis Title: The specificity and evolution of gene regulatory elements
Publications while at MIT:
1. MicroRNA target finding by comparative genomics.
Friedman RC, Burge CB.
Methods Mol Biol. 2014;1097:457-76. doi: 10.1007/978-1-62703-709-9_21. Review. PMID:24639172
2. Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument.
Nutiu R, Friedman RC, Luo S, Khrebtukova I, Silva D, Li R, Zhang L, Schroth GP, Burge CB.
Nat Biotechnol. 2011 Jun 26;29(7):659-64. doi: 10.1038/nbt.1882.PMID:21706015 Free PMC Article
Bandyopadhyay S, Friedman RC, Marquez RT, Keck K, Kong B, Icardi MS, Brown KE, Burge CB, Schmidt WN, Wang Y, McCaffrey AP.
J Infect Dis. 2011 Jun 15;203(12):1753-62. doi: 10.1093/infdis/jir186. PMID:21606534 Free PMC Article
4. Formation, regulation and evolution of Caenorhabditis elegans 3’UTRs.
Jan CH, Friedman RC, Ruby JG, Bartel DP.
Nature. 2011 Jan 6;469(7328):97-101. doi: 10.1038/nature09616. Epub 2010 Nov 17.PMID:21085120 Free PMC Article
5. Most mammalian mRNAs are conserved targets of microRNAs.
Friedman RC, Farh KK, Burge CB, Bartel DP.
Genome Res. 2009 Jan;19(1):92-105. doi: 10.1101/gr.082701.108. Epub 2008 Oct 27.PMID:18955434 Free PMC Article