Doctoral Thesis Title: Exploring the regulatory rolesroles of microRNAs in mammalian development
Publications while at MIT:
Genome-wide impact of a recently expanded microRNA cluster in mouse.
Zheng GX, Ravi A, Gould GM, Burge CB, Sharp PA.
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15804-9. doi: 10.1073/pnas.1112772108. Epub 2011 Sep 12.PMID:21911408 Free PMC Article
MicroRNAs can generate thresholds in target gene expression.
Mukherji S, Ebert MS, Zheng GX, Tsang JS, Sharp PA, van Oudenaarden A.
Nat Genet. 2011 Aug 21;43(9):854-9. doi: 10.1038/ng.905.PMID:21857679 Free PMC Article
A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells.
Zheng GX, Ravi A, Calabrese JM, Medeiros LA, Kirak O, Dennis LM, Jaenisch R, Burge CB, Sharp PA.
PLoS Genet. 2011 May;7(5):e1002054. doi: 10.1371/journal.pgen.1002054. Epub 2011 May 5. PMID:21573140 Free PMC Article
Leung AK, Young AG, Bhutkar A, Zheng GX, Bosson AD, Nielsen CB, Sharp PA.
Nat Struct Mol Biol. 2011 Feb;18(2):237-44. doi: 10.1038/nsmb.1991. Epub 2011 Jan 23. Erratum in: Nat Struct Mol Biol. 2011 Sep;18(9):1084. PMID:21258322 Free PMC Article
Dynamic regulation of miRNA expression in ordered stages of cellular development.
Neilson JR, Zheng GX, Burge CB, Sharp PA.
Genes Dev. 2007 Mar 1;21(5):578-89.PMID:17344418 Free PMC Article