Advanced Electives

A requirement of four advanced electives is designed to develop both breadth and depth for students in the CSB PhD Program. These should be 12-unit G-level graduate subjects. The electives add to the base of the core curriculum and contribute strength in areas related to student interest and research direction. Two of the four restricted electives must be in the same area (department). At least one of the electives must be from an engineering discipline and at least one from a biology-related field.

As is typical for students in other doctoral programs at MIT, CSB PhD students may take classes beyond the required restricted electives. These additional subjects might be useful to explore advanced topics important for thesis research in later years.

Each student will design a program of advanced electives that satisfies the distribution and area requirements in close consultation with members of the CSB PhD Graduate Committee and with their thesis advisor. Examples of combinations of courses that might be particularly appropriate for students with certain interests are described below. These examples are intended as illustrations only – individual programs will vary.

Students with an interest in model building and theory might include Network Optimization (Computer Science/Operations Research) and/or Foundations of Algorithms for Computational Biology (Computer Science/Biological Engineering).

Students with a focus on developing novel tools might select subjects such as Integrated Microelectronic Devices (Electrical Engineering/Materials Science) and/or Fundamental Limits of Biological Measurement (Biological Engineering).

Students who intend to pursue computational biology or bioinformatics can take courses in Computational Functional Genomics (Biology, Computer Science), Bioinformatics: Principles, Applications, and Methods (Chemical Engineering), or Biomedical Information Technology (Mechanical Engineering).

The following is a list of subjects that students may consider for advanced electives or additional subjects, organized by department. See the MIT online subject descriptions for more information.

(Not a complete list. Please petition the committee if there is an unlisted 12-unit, G-Level course you wish to take.)

* All courses are offered in-person for Fall 2022 and Spring 2023. All courses must be taken for a letter grade.

Civil and Environmental Engineering

1.685/2.034/18.377J Nonlinear Dynamics and Waves (Not offered 2022-2023)

1.89 Earth's Microbiomes (Spring 2023, G, 12 units, O. Cordero)

1.881/HST.538J (Spring 2023, G, 12 units, T. Lieberman)

 

Mechanical Engineering

2.18 Biomolecular Feedback Systems (Spring 2023, G, 12 units, Del Vecchio)

2.717 Optical Engineering (Spring 2023, G, 12 units, Staff)

 

Chemistry

5.64/HST.539J Frontiers of Interdisciplinary Science in Human Health and Disease (Spring 2023, G, 12 units, X. Wang)

5.70/10.546J Statistical Thermodynamics (Fall 2022, G, 12 units, B. Zhang) 

 

Electrical Engineering and Computer Science

6.C51 Modeling with Machine Learning: from Algorithms to Applications (Spring 2023, G, 6 units, R.Barzilay, T. Jaakkola) MUST BE TAKEN WITH:

20.C51/3.C51/10.C51J Machine Learning for Molecular Engineering (Spring 2023, G, 6 units, R. Gomez-Bombarelli, C. Coley, E. Fraenkel)

6.3702 Introduction to Probability  (Fall 2022/ Spring 2023, G, 12 units, Fall: L. Zheng, Spring: G. Bresler)

6.3722 Introduction to Statistical Data Analysis (Spring 2023, G, 12 units, Y. Polyanskiy, D. Shah, J. N. Tsitsiklis)

6.5150 Large-scale Symbolic Systems (Spring 2023, G, 12 units, G. J. Sussman)

6.5210/18.415J Advanced Algorithms (Fall 2022, G, 12 units, D. Karger)

6.5420 Randomness and Computation (Not offered 2022-2023, G, 12 units)

6.6220 Power Electronics (Spring 2023, G, 12 units, Staff)

6.6500/3.43J Integrated Microelectronic Devices (Fall 2022, G, 12 units, J. Del Alamo)

6.7100/6.338J Dynamic Systems and Control (Spring 2023, G, 12 units, Staff)

6.7300/2.096/16.910J Introduction to Modeling and Simulation (Fall 2022, G, 12 units, L. Daniel)

6.7310/18.335J Introduction to Numerical Methods (Spring 2023, G, 12 units, Staff)

6.7330/2.097/16.920J Numerical Methods for Partial Differential Equations (Fall 2022, G, 12 units, J. Peraire)

6.7700/15.085J Fundamentals of Probability (Fall 2022, G, 12 units, J. Tsitsiklis)

6.7710 Discrete Stochastic Processes (Spring 2023, G, 12 units, Staff)

6.7720/15.070J Discrete Probability and Stochastic Process (Spring 2023, G,12, D. Gamarnik)

6.7800 Inference and Information (Spring 2023, G, 12 units, Staff)

6.7810 Algorithms for Inference (Fall 2022, G, 12 units, G.Bresler)

6.7830 Bayesian Modeling and Inference (Spring 2023, G, 12 units, Staff)

6.7900 Machine Learning (Fall 2022, G, 12 units, T. Jaakkola)

6.7930/HST.956 [J] Machine Learning for Healthcare (Spring 2023, G, 12 units, D. Sontag, P.Szolovits)

6.8610 Quantitative Methods for Natural Language Processing ( Fall 2022, G, 12 units, Y. Kim)

6.8700/HST.507J Advanced Computational Biology: Genomes, Networks, Evolution (Fall 2022, G, 12 units, M. Kellis) [Could also be used to satisfy Comp Bio requirement]

6.8710/HST.506 [J] Computational Systems Biology: Deep Learning in the Life Sciences (Spring 2023, G, 12 units, Staff) [Could also be used to satisfy Comp Bio requirement]

 

Biology

7.493/ 1.87/ 12.493/ 20.446J Microbial Genetics and Evolution (Fall 2022, G, 12 units, A. D. Grossman, O. Cordero)

7.60 Cell Biology: Structure and Functions of the Nucleus (Spring 2023, G, 12 units, L. Boyer, R. Young, Staff)

7.61/20.561J Eukaryotic Cell Biology: Principles and Practice (Fall 2022, G, 12 units, M. Krieger, Staff) [Could also be used to satisfy Bio requirement]

7.63/ 20.630J Immunology (Spring 2023, G, 12 units, S. Spranger, M. Birnbaum) [Could also be used to satisfy Bio requirement]

7.64 Molecular Mechanisms, Pathology and Therapy of Human Neuromuscular Disorders (Not offered 2022-2023, G, 12 units, D. Housman)

7.66 Molecular Basis of Infectious Disease (Spring 2023, G, 12 units, R. Lamason, S. Lourido)

7.69/ 9.181J Developmental Neurobiology (Spring 2023 G, 12 units, Staff)

7.70 Regulation of Gene Expression (Not offered 2022-2023, G, 12 units, Staff)

7.71 Biophysical Technique (Spring 2023, G, 12 units, T. Schwartz)

7.72 Stem Cells, Regeneration, and Development (Not offered 2022-2023, G, 12 units,  R. Jaenisch, P. Reddien)

7.73 Principles of Chemical Biology (Not offered 2022-2023, G, 12 units, B. Imperiali, J.K. Weng)

7.75 Human Genetics and Genomics (Spring 2023, G, 12 units, D. Page) 

7.77 Nucleic Acids, Structure, Function, Evolution and Their Interactions with Proteins (Spring 2023, G, 12 units, D. Bartel, A. Jain)

7.85 The Hallmarks of Cancer (Fall 2022, G, 12 units, M. Hemann, T. Jacks)

7.86 Building with Cells (Fall 2022, G, 12 units, L. Boyer, P. Li)

7.95 Cancer Biology (Spring 2023, G, 12 units, R. Weinberg, O. Yilmaz)

 

Physics

8.333 Statistical Mechanics I (Fall 2022, G, 12 units, S. Todadri)

8.334 Statistical Mechanics II (Spring 2023, G, 12 units, M. Kardar)

8.431/6.6340J Nonlinear Optics (Spring 2023, G, 12 units, Staff)

8.591/7.81J Systems Biology (Fall 2022, G, 12 units, J. Gore) [Could also be used to satisfy Comp Bio requirement]

8.592/HST.452J Statistical Physics in Biology (Not offered 2022-2023, G, 12 units, Staff)

8.593/HST.450J Biological Physics (Spring 2023 G, 12 units, Staff)

 

Brain and Cognitive Sciences

9.013/7.68J Molecular and Cellular Neuroscience Core II (Spring 2023, G, 12 units, Staff) [Could also be used to satisfy Bio requirement]

9.015/7.65J Molecular and Cellular Neuroscience Core I (Fall 2022, G, 12 units, J. T. Littleton, M.Sheng)

9.520/6.7910J Statistical Learning Theory and Applications (Fall 2022, G, 12 units, T. Poggio)

 

Chemical Engineering

10.544 Metabolic and Cell Engineering (Fall 2022, Spring 2023, G, 12 units, Staff)

10.555/HST.940J Bioinformatics: Principles, Methods, and Applications  (Spring 2023, G, 12 units, Staff)

10.557 Mixed-integer and Nonconvex Optimization (Spring 2023, G, 12 units, P. I. Barton)

 

Aeronautics and Astronautics

16.940 Numerical Methods for Stochastic Modeling and Inference Fall 2022, G, 12 units, Y.M. Marzouk)

16.391/6.434JStatistics for Engineers and Scientists (Fall 2022, G, 12 units, Staff)

 

Mathematics

18.0651 Matrix Methods in Data Analysis, Signal Processing, and Machine Learning (Spring 2023, G, 12 units, S.G. Johnson)

18.0751 Methods for Scientists and Engineers (Spring 2023, G, 12 units, H. Cheng)

18.0851 Computational Science and Engineering I (Fall 2022, Spring 2023, G, 12 units, P.T. Choi)

18.0861 Computational Science and Engineering II (Spring 2023, G, 12 units, Staff)

18.408 Topics in Theoretical Computer Science (Fall 2022, Spring 2023, G, 12 units, D. Minzer, A. Moitra)

18.417 Introduction to Computational Molecular Biology (Spring 2023, G, 12 Units, B.Berger)

18.418/HST.504J Topics in Computational Molecular Biology (Fall 2022, G, 12 units, B. Berger)

18.4531 Combinatorial Optimization (Spring 2023, G, 12 units, Staff)

18.455 Advanced Combinatorial Optimization (Not offered 2022-2023, G, 12 units, M. X. Goemans)

18.6501 Fundamentals of Statistics (Fall 2022, Spring 2023, G, 12 units, P. Rigollet, P.Ghosal)

18.677 Topics in Stochastic Processes (Spring 2023, G, 12 units, A. Borodin)

 

Biological Engineering

20.201 Fundamentals of Drug Development (Fall 2022, Spring 2023, G, 12 units, P. C. Dedon, R. Sasisekharan)

20.405/6.8720J Principals of Synthetic Biology (Fall 2022, G, 12 units, R. Weiss)

20.409 Biological Engineering II: Instrumentation and Measurement (Fall 2022, Spring 2023, G, 12 units, E. Boyden, A. Jasanoff, P. So, M. Jonas, J. Sutton, S. Wasserman)

20.410/2.798/3.971/6.524/10.537J Molecular, Cellular, and Tissue Biomechanics ( Not offered 2022-2023, G, 12 units, M. Bathe, K. Ribbeck, P. So)

20.415 Physical Biology (Spring 2023, G, 12 units, Satff)

20.420/10.538J Principles of Molecular Bioengineering (Fall 2022, G, 12 units, A. Jasonoff, E. Fraenkel)

20.430/ 2.795/6.4832/10.539J Fields, Forces, and Flows in Biological Systems   (Fall 2022, G, 12 units, M. Bathe, A. Hansen)

20.440 Analysis of Biological Networks (Spring 2023, G, 15 units, B. Bryson, P. Blainey)

20.463/3.963J Biomaterials Science and Engineering (Fall 2022, G, 12 units, D. Irvine, K. Ribbeck)

20.490 Computational Systems Biology: Deep Learning in the Life Sciences (Not offered 2022-2023) [Could also be used to satisfy Comp Bio requirement]

20.535/10.535J Protein Engineering (Spring 2023, G, 12 units, K.D. Wittrup, B. Tidor) 

 

Institute for Data, Systems, and Society

IDS.136/6.7820J Graphical Models: A Geometric, Algebraic, and Combinatorial Perspective (Not offered 2022-2023 G, 12 units, C. Uhler)

IDS.147/15.077J Statistical Machine Learning and Data Science (Spring 2023, G, 12 units, R. Welsch)

 

Health Sciences and Technology

HST.035 Pathology of Human Disease (Spring 2023, G, 16 units, S. Lovitch)

HST.176 Cellular and Molecular Immunology (Fall 2022, G, 12 units, S. Pillai, B. Cherayil)

HST.508 Evolutionary and Quantitative Genomics (Fall 2022, G, 12 units, L. Mirny, T. Lieberman)