Anna Podgornaia, Ph.D.

Year of Graduation: 



Prof. Michael Laub

Current Position: 

Senior Principal Scientist, Bristol Myers Squibb

Doctoral Thesis Title: Pervasive degeneracy and epistasis in a protein-protein interface


Publications while at MIT: 

1. The small membrane protein MgrB regulates PhoQ bifunctionality to control PhoP target gene expression dynamics.

Salazar ME, Podgornaia AI, Laub MT.

Mol Microbiol. 2016 Nov;102(3):430-445. doi: 10.1111/mmi.13471. Epub 2016 Aug 25.

PMID: 27447896


2. Protein evolution. Pervasive degeneracy and epistasis in a protein-protein interface.

Podgornaia AI, Laub MT.

Science. 2015 Feb 6;347(6222):673-7. doi: 10.1126/science.1257360.

PMID: 25657251


3. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling.

Podgornaia AI, Casino P, Marina A, Laub MT.

Structure. 2013 Sep 3;21(9):1636-47. doi: 10.1016/j.str.2013.07.005. Epub 2013 Aug 15.

PMID: 23954504


4. Determinants of specificity in two-component signal transduction.

Podgornaia AI, Laub MT.

Curr Opin Microbiol. 2013 Apr;16(2):156-62. doi: 10.1016/j.mib.2013.01.004. Epub 2013 Jan 24. Review.

PMID: 23352354