Jonathan Rameseder Ph.D.

Year of Graduation: 



Prof. Michael Yaffe

Current Position: 

Patent Examiner at the European Patent Office

Thesis Title:  Multivariate methods for the statistical analysis of hyperdimensional high-content screening data 

Publications While at MIT:


1.A Multivariate Computational Method to Analyze High-Content RNAi Screening Data.

Rameseder J, Krismer K, Dayma Y, Ehrenberger T, Hwang MK, Airoldi EM, Floyd SR, Yaffe MB.

J Biomol Screen. 2015 Sep;20(8):985-97. doi: 10.1177/1087057115583037. Epub 2015 Apr 27.

PMID:25918037 Free PMC Article


2. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer.

Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J,Chen CC, D'Andrea AD, Kozono D.

PLoS One. 2013 Sep 5;8(9):e73710. doi: 10.1371/journal.pone.0073710. eCollection 2013.

PMID:24040035 Free PMC Article


3. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.

Floyd SR, Pacold ME, Huang Q, Clarke SM, Lam FC, Cannell IG, Bryson BD, Rameseder J, Lee MJ, Blake EJ, Fydrych A, Ho R, Greenberger BA, Chen GC, Maffa A, Del Rosario AM, Root DE, Carpenter AE, Hahn WC, Sabatini DM, Chen CC, White FM, Bradner JE, Yaffe MB.

Nature. 2013 Jun 13;498(7453):246-50. doi: 10.1038/nature12147. Epub 2013 Jun 2.

PMID:23728299 Free PMC Article


4. Pride-asap: automatic fragment ion annotation of identified PRIDE spectra.

Hulstaert N, Reisinger F, Rameseder J, Barsnes H, Vizcaíno JA, Martens L.

J Proteomics. 2013 Dec 16;95:89-92. doi: 10.1016/j.jprot.2013.04.011. Epub 2013 Apr 17.

PMID:23603108 Free PMC Article


5. Systematic phosphorylation analysis of human mitotic protein complexes.

Hegemann B, Hutchins JR, Hudecz O, Novatchkova M, Rameseder J, Sykora MM, Liu S, Mazanek M, Lénárt P, Hériché JK, Poser I, Kraut N, Hyman AA, Yaffe MB, Mechtler K, Peters JM.

Sci Signal. 2011 Nov 8;4(198):rs12. doi: 10.1126/scisignal.2001993.

PMID:22067460 Free PMC Article


6. Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome.

Grosstessner-Hain K, Hegemann B, Novatchkova M, Rameseder J, Joughin BA, Hudecz O, Roitinger E, Pichler P, Kraut N, Yaffe MB, Peters JM, Mechtler K.

Mol Cell Proteomics. 2011 Nov;10(11):M111.008540. doi: 10.1074/mcp.M111.008540. Epub 2011 Aug 21.

PMID:21857030 Free PMC Article


7. The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM.

Science. 2011 Jun 10;332(6035):1317-22. doi: 10.1126/science.1199498.

PMID:21659604 Free PMC Article