Maxim Wolf Ph.D.

Year of Graduation: 

2019

Advisors/Lab: 

Prof. Manolis Kellis

Current Position: 

Research Associate, Harvard Medical School Department of Biomedical Informatics; Boston, MA

Thesis Title: Evolutionary and structural signatures of protein-coding function; synonymous acceleration, read-through, and structural impact of mutations

 

Publications while at MIT: 

1. Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy.

Kousi M, Söylemez O, Ozanturk A, Mourtzi N, Akle S, Jungreis I, Muller J, Cassa CA, Brand H, Mokry JA, Wolf MY, Sadeghpour A, McFadden K, Lewis RA, Talkowski ME, Dollfus H, Kellis M, Davis EE, Sunyaev SR, Katsanis N.Nat Genet. 2020 Nov;52(11):1145-1150. doi: 10.1038/s41588-020-0707-1. Epub 2020 Oct 12.PMID: 33046855

 

2. Perspectives on ENCODE.

ENCODE Project Consortium, Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM.Nature. 2020 Jul;583(7818):693-698. doi: 10.1038/s41586-020-2449-8. Epub 2020 Jul 29.PMID: 32728248 Free PMC article.

 

3. FRESCo: finding regions of excess synonymous constraint in diverse viruses.

Sealfon RS, Lin MF, Jungreis I, Wolf MY, Kellis M, Sabeti PC.Genome Biol. 2015 Feb 17;16(1):38. doi: 10.1186/s13059-015-0603-7.PMID: 25853568 Free PMC article.