CSB Thesis Defense
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Copy of CSB Ph.D. Thesis Defense: Alex LeNail (Heiman Lab)
Read more: Copy of CSB Ph.D. Thesis Defense: Alex LeNail (Heiman Lab)Date: Friday, May 2,2025 Time: 2:00 3:00 PM Room: Singleton Auditorium (46-3002) CSB Ph.D. Candidate: Alex LeNail Supervisor: Myriam Heiman (BCS, Picower) TDC Members: Jonathan Weissman Manolis Kellis Hongkui Zeng Title: Transcriptional Reprogramming to Reverse Aging-Associated Transcriptional Dysregulation in Neurons Abstract: It is unclear what the mechanistic contribution of normal aging is to the neurodegenerative diseases that present in advanced age. This…
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CSB Ph.D. Thesis Defense: Jide Ezike (Getz Lab)
Read more: CSB Ph.D. Thesis Defense: Jide Ezike (Getz Lab)Date: Friday, April 18, 2025 Time: 12:00 -1:00 PM Room: Yellowstone room in Broad Institute CSB Ph.D. Candidate: Jide Ezike Supervisor: Gad Getz TDC Members: Jonathan Weissman (chair) Aviv Regev Caroline Uhler Mario Suva Title: Applications of Native and Engineered Genetic Barcodes in Single-Cell RNA-Seq to Study Clonal Evolution and Cellular Phenotypic Diversity Abstract: Cells are constantly altering their states, whether due to…
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CSB Ph.D. Thesis Defense: Vikram Sundar (Esvelt Lab)
Read more: CSB Ph.D. Thesis Defense: Vikram Sundar (Esvelt Lab)Date: Wednesday, May 7, 2025 Time: 1:00 -2:00 PM Room: E15-359 CSB Ph.D. Candidate: Vikram Sundar Supervisor: Kevin M. Esvelt (Associate Professor of Media Arts and Sciences, NEC Career Development Professor of Computer and Communications, Media Lab) TDC Members: Amy Keating, Jeff Gore, Sergey Ovchinnikov, Debora Marks (external) Title: Engineering TEV Protease Specificity: An Exploration of Machine Learning and High-Throughput Experimentation for Protein…
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CSB Ph.D Thesis Defense: Christopher Rodriguez (Reddien Lab)
Read more: CSB Ph.D Thesis Defense: Christopher Rodriguez (Reddien Lab)Date: Thursday, April 10, 2025 Time: 2:00 -3:00 PM Location: Whitehead Auditorium CSB Ph.D. Candidate: Christopher Rodriguez Advisor: Peter Reddien TDC Members: TDC Members: David Page, David Bartel, Vadim Gladyshev (external) Title: The Limits of Longevity Abstract: Do all animals age? Although aging seems to be a widespread phenomenon, some demographic studies have failed to find evidence of aging in certain…
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CSB Ph.D. Thesis Defense: Ivy Liu (Shalek Lab)
Read more: CSB Ph.D. Thesis Defense: Ivy Liu (Shalek Lab)Date: Wednesday, April 30th, 2025 Time: 1-2pm Room: Ragon Auditorium CSB Ph.D. Candidate: Ivy Liu Advisor: Alex Shalek (Chemistry, IMES/Broad/Ragon) TDC Members: Forest White (chair), Ernest Fraenkel, Srivatsan Raghavan (external) Title: Decoding Disease Drivers Through Single-Cell Omics and Scalable Phenotypic Screens Abstract: High-throughput phenotypic screens using biochemical perturbations and high-content readouts are constrained by limitations of scale. In…
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CSB PhD Thesis Defense: Kamal Maher (Xiao Wang Lab)
Read more: CSB PhD Thesis Defense: Kamal Maher (Xiao Wang Lab)Date: Friday, April 25th, 2025 Time: 10-11 am Room: 68-181 CSB PhD Candidate: Kamal Maher Advisor: Xiao Wang (Chemistry, Broad) TDC Members: Peter Reddien (chair) Alex Shalek, Fabian Theis (external) Title: Fundamental representations of regions and interactions in spatial transcriptomics Abstract: While cells are often considered the fundamental unit of biology, it is their spatial…
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CSB Thesis Defense
Read more: CSB Thesis DefenseStudent: Peter Freese Lab: Burge Title: “Biochemical and Functional Characterization of Human RNA Binding Proteins” RNA not only shuttles information between DNA and proteins but also carries out many other essential cellular functions controlled by approximately one thousand RNA binding proteins (RBPs). In this thesis, I describe the affinity landscapes of the largest set of human…
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Student: Vincent Xue
Read more: Student: Vincent XueStudent: Vincent Xue Lab: Keating Title: Modeling and Designing Bcl-2 Family Protein Interactions Using High-Throughput Interaction Data Protein-protein interactions (PPIs) play a major role in cellular function, mediating signal processing, and regulating enzymatic activity. Given the importance of protein interactions in the cell, understanding how proteins interact is essential for prediction of new binding partners,…
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CSB Thesis Defense Miriam Shiffman (Broderick & Regev Labs)
Read more: CSB Thesis Defense Miriam Shiffman (Broderick & Regev Labs)CSB PhD Candidate: Miriam Shiffman Faculty Advisor: Tamara Broderick & Aviv Regev Committee members: Stefanie Jegelka, Allon Klein, Ashia Wilson Date: Tuesday January 16, 2024 Time: 12:00 PM EST Thesis title: Uncertainty & robustness for single-cell studies: Could dropping a few cells change the takeaways from differential expression? Abstract: The advent of new technologies capable…
Upcoming Events
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CSB Ph.D. Thesis Defense: Jide Ezike (Getz Lab)
View Event Details: CSB Ph.D. Thesis Defense: Jide Ezike (Getz Lab)Date: Friday, April 18, 2025 Time: 12:00 -1:00 PM Room: Yellowstone room in…
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CSB Ph.D Thesis Defense: Christopher Rodriguez (Reddien Lab)
View Event Details: CSB Ph.D Thesis Defense: Christopher Rodriguez (Reddien Lab)Date: Thursday, April 10, 2025 Time: 2:00 -3:00 PM Location: Whitehead Auditorium CSB…