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CSB Thesis Defense

  • CSB Thesis Defense

    Jacob Witten Ribbeck lab Title: “Molecular characterization of mucus binding” Abstract: Binding of small molecules to mucus membranes in the body has an important role in human health, as it can affect the diffusivity and activity of any molecule that acts in a mucosal environment. The binding of drugs and of toxins and signaling molecules from…

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  • CSB Thesis Defense

    The Computational and Systems Biology PhD Program is proud to announce the following thesis defense: Jonathan Teo Sarpeshkar Lab Date: Thursday May 16, 2019, 3PM Room: 36-428 Title: Synthetic Analog Feedback Control Circuits in Living Cells Abstract Models of biochemical reaction networks in cells are important for advancing our understanding of complex biological systems and…

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  • CSB Thesis Defense

    Joy Yang Martin Polz Lab Title: Statistically Identifying Mechanisms of Phage-Host Interactions Abstract: Bacteriophage and their hosts are locked in an age-old arms race. Successful bacteria are subject to predation, forcing the population to diversify, and phage are also quick to adapt tactics for infecting these potential hosts. Sampling of closely related bacterial strains that differ…

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  • CSB Thesis Defense

    Nezar Abdennur Mirny Lab  Title: Unfolding genome organization interphase Abstact:  Contact frequency maps from high throughput chromosome conformation capture technologies have revealed several organizing patterns for mammalian interphase chromosomes, including self-interacting topologically associating domains (TADs) which are believed to function as insulating gene regulatory neighborhoods. However, the mechanisms driving these patterns are still unknown. In this…

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  • CSB Thesis Defense

    Colette L. Picard Gehring Lab Title: Dynamics of DNA methylation and genomic imprinting in Arabidopsis Abstract: DNA methylation is an epigenetic mark that is highly conserved and important in diverse cellular processes, ranging from transposon silencing to genomic imprinting. In plants, DNA methylation is both mitotically and meiotically heritable, and changes in DNA methylation can be…

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  • CSB Thesis Defense

    Mariana Matus GarciaAlm  LabDate: Monday June 4, 2018Time: 10AMLocation:  Building 68 room 121Title: Analysis of fecal biomarkers to impact clinical care and public health Abstract: In this thesis, I explore the potential of fecal biomarkers to impact clinical care and public health. First, I highlight the potential of the gut microbiome to provide novel diagnostic and therapeutic…

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  • CSB Thesis Defense: Sameed Siddiqui (Sabeti/Collins Lab)

    Posted:
    June 6, 2024

    CSB PhD Candidate: Sameed Siddiqui  Faculty Advisors: Prof. Pardis Sabeti & Prof. James Collins Date: Friday, June 7, 2024 Time: 2:00 PM EST Room: 68-181 Thesis title: Serology, CRISPR Diagnostics, and Machine Learning Architectures for Biological Sequences Abstract: Fueled by technological breakthroughs, advancements in our understanding of infectious agents offer unprecedented potential for their early detection, intervention, and ultimately, eradication. This…

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  • CSB Thesis Defense: Cameron Flower (White Lab)

    Posted:
    April 25, 2024

    CSB PhD Candidate: Cameron Flower Faculty Advisor: Prof. Forest White Date: Friday April 26, 2024 Time: 1:00 PM EST Thesis title: Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition Abstract: Therapeutics targeting oncogenic kinases have offered longer survival and superior quality of life for cancer patients with particular malignancies compared to the preceding standard of care. However,…

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  • CSB Thesis Defense Samuel Goldman (Coley Lab)

    Posted:
    January 11, 2024

    CSB PhD Candidate: Samuel Goldman Faculty Advisor: Prof. Connor Coley (Chem E) Date: January 12th, 2024 Time: 11:00 AM – 12:00 PM Eastern Time Location: MIT Stata Center Room 32-155 Thesis title: Machine Learning Methods for Discovering Metabolite Structures from Mass Spectra Abstract: Small molecule metabolites mediate myriads of biological and environmental phenomena across host-microbiome interactions, plant chemistry, cancer biology, and…

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