The Young laboratory is interested in the transcriptional control of cell identity and differentiation in mice and humans. They use experimental and computational technologies to determine how signaling pathways, transcription factors, chromatin regulators and small RNAs control gene expression programs in healthy and diseased cells. Their interests range from the basic molecular mechanisms of gene control to development of drugs for cancer and other diseases caused by gene mis-regulation, using a combination of molecular genetic and genomic tools and approaches.