News & Events

  • Engineering “capture compounds” to probe cell growth

    Posted:
    December 17, 2018
    Laub Bacteria-starvation-response-research-ppGpp-image-MIT-00_0

    Researchers develop a method to investigate how bacteria respond to starvation and to identify which proteins bind to the "magic spot" – ppGpp.  In 1969, scientist Michael Cashel was analyzing the compounds produced by starved bacteria when he noticed two spots appearing on his chromatogram as if by magic. Today, we know one of these…

    Read more: Engineering “capture compounds” to probe cell growth
  • Computer model offers more control over protein design

    Posted:
    November 5, 2018
    MIT-Protein-Design_0

    New approach generates a wider variety of protein sequences optimized to bind to drug targets. Designing synthetic proteins that can act as drugs for cancer or other diseases can be a tedious process: It generally involves creating a library of millions of proteins, then screening the library to find proteins that bind the correct target.…

    Read more: Computer model offers more control over protein design
  • Our microbes are starving, and that’s a good thing

    Posted:
    October 29, 2018
    SwampGut_HeroCover

    High-protein diet, antibiotics make gut a festering swamp. Each of us is only half human. The other half is microbial. Trillions of viruses, fungi, bacteria and other microscopic organisms coat our skin and line our vital organs. We depend on these microbial communities, collectively known as our microbiome, to digest food, synthesize vitamins, bolster immune…

    Read more: Our microbes are starving, and that’s a good thing

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