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Computational method for screening drug compounds can help predict which ones will work best against tuberculosis or other diseases. Machine learning is a computational tool used by many biologists to analyze huge amounts of data, helping them to identify potential new drugs. MIT researchers have now incorporated a new feature into these types of machine-learning…

  A well-known protein family binds to many more RNA sequences than previously thought in order to help neurons grow. In every cell, RNA-binding proteins (RBPs) help tune gene expression and control biological processes by binding to RNA sequences. Researchers often assume that individual RBPs latch tightly to just one RNA sequence. For instance, an…

ENCODE consortium identifies RNA sequences that are involved in regulating gene expression.   The human genome contains about 20,000 protein-coding genes, but the coding parts of our genes account for only about 2 percent of the entire genome. For the past two decades, scientists have been trying to find out what the other 98 percent…