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Uncovering how cells control their protein output
Read more: Uncovering how cells control their protein outputGene-Wei Li investigates the rules that cells use to maintain the correct ratio of the proteins they need to survive. A typical bacterial genome contains more than 4,000 genes, which encode all of the proteins that the cells need to survive. How do cells know just how much of each protein they need for their…
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A new control system for synthetic genes
Read more: A new control system for synthetic genesResearchers have developed a technique that could help fine-tune the production of monoclonal antibodies and other useful proteins. Using an approach based on the CRISPR gene-editing system, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells. Credits: Cell image: Matthew Daniels, edited…
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Biologists glean insight into repetitive protein sequences
Read more: Biologists glean insight into repetitive protein sequencesA computational analysis reveals that many repetitive sequences are shared across proteins and are similar in species from bacteria to humans. MIT researchers used a technique called dot-plot matrix, which is a way to visually represent amino acid sequences, to compare protein sequences known as “low-complexity regions” across many different species. Credits:Image: Courtesy of the…
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