Cover Photo Credit: Dr. Soohong Kim & Dr. Paul Blainey, Image Credit: Boyden Lab
Research in Bioengineering and Neuroengineering at MIT emphasizes development of innovative tools to enable high-resolution measurements, high-precision control, and high-throughput perturbation of biological systems, including photogenetics and genome engineering.
MIT engineers’ new technique analyzes the 3D organization of the genome at a resolution 100 times higher than before.
Image: Melanie Gonick/MIT
Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from the target.
CSB PhD Candidate: Adam Atanas
Advisor: Prof. Steven Flavell
Title: "Brain-wide representations of behavior spanning multiple timescales and states in C. elegans"
Researchers have developed a technique that could help fine-tune the production of monoclonal antibodies and other useful proteins.
A machine-learning method finds patterns of health decline in ALS, informing future clinical trial designs and mechanism discovery. The technique also extends to Alzheimer’s and Parkinson’s.