Illustration Credit: Jose-Luis Olivares/MIT
Image Credit: Manalis, Lauffenburger, and Shalek labs
Research in Cancer Systems Biology at MIT emphasizes mechanistic understanding of oncogenesis and cancer progression through integration of large-scale –omic data, and single cell analysis
The substance that bathes tumors in the body is quite different from the medium used to grow cancer cells in the lab, biologists report.
New approach generates a wider variety of protein sequences optimized to bind to drug targets.
Designing synthetic proteins that can act as drugs for cancer or other diseases can be a tedious process: It generally involves creating a library of millions of proteins, then screening the library to find proteins that bind the correct target.
Matthew Vander Heiden seeks new cancer treatments that exploit tumor cells' abnormal metabolism
Shortfall of digestive enzymes can lead to tissue breakdown in early stages of pancreatic cancer.
Study in worms reveals gene loss can lead to accumulation of waste products in cells.
Synthetic Biologist hopes to develop treatments for cancer and other diseases.
In high school and college, Timothy Lu spent a lot of time programming computers. But as his college graduation approached, he turned his attention toward programming biological systems. The field of synthetic biology was just beginning to emerge, and he wanted to be part of it.