Student: Amanda Kedaigle
Lab: Fraenkel
Title: Integrating Omics Data: A new Software Tool and its Use in Implicating Therapeutic Targets in Huntington's Disease
Chemical Biology and Metabolomics
Image Credit: Lucas Sullivan, Vander Heiden Lab
Research in Chemical Biology and Metabolomics at MIT aims to discover small molecules and chemical modifications of macromolecules that regulate metabolism, cell signaling, and homeostasis and to model aspects of cellular metabolism.
Scientists find different cell types contain the same enzyme ratios
New discovery suggest that all life may share a common design principle.
Scientists deliver high-resolution glimpse of enzyme structure
New finding suggests differences in how humans and bacteria control production of DNA's building blocks.
Using a state-of-the-art type of electron microscopy, an MIT-led team has discovered the structure of an enzyme that is crucial for maintaining an adequate supply of DNA building blocks in human cells.
Matthew Vander Heiden
Researchers establish long-sought source of ocean methane
An abundant enzyme in marine microbes may be responsible for production of the greenhouse gas.
Ed Boyden
Catherine L. Drennan
Heather J. Kulik
Michael T. Laub
Christopher A. Voigt
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