Photo Credit: Shicong Xie
Research in Quantitative Imaging at MIT develops and applies novel optical, biochemical, and computational methods (e.g., expansion microscopy, single molecule measurements) to resolve the spatiotemporal dynamics of biological systems at scales spanning the molecular, cellular, and organismal levels.
His technology platforms have benefited genomics, diagnostics and drug screening.
Microfluidics — the science of manipulating tiny amounts of fluid through channels — has been widely used in fields such as genomics, where it has helped to enable high-speed sequencing. Several years ago, Paul Blainey started to wonder why microfluidics was not used for drug screening, another application that requires analyzing huge amounts of samples quickly.
An algorithm developed to study the structure of galaxies helps explain a key feature of embryonic development.
As embryos develop, they follow predetermined patterns of tissue folding, so that individuals of the same species end up with nearly identically shaped organs and very similar body shapes.
New 3-D imaging technique can reveal, much more quickly than other methods, how neurons connect throughout the brain.