2020

Doctoral Thesis Title: Computational methods for studying cellular differentiation using single-cell RNA-sequencing Publications while at MIT: A Multiplexed Barcodelet Single-Cell RNA-Seq Approach Elucidates Combinatorial Signaling Pathways that Drive ESC Differentiation. Yeo GHT, Lin L, Qi CY, Cha M, Gifford DK, Sherwood RI.Cell Stem Cell. 2020 Jun 4;26(6):938-950.e6. doi: 10.1016/j.stem.2020.04.020. Epub 2020 May 26.PMID: 32459995

Doctoral Thesis Title: Biochemically informed modeling of miRNA targeting efficacy Publications while at MIT: 1.The biochemical basis of microRNA targeting efficacy Sean E. McGeary, Kathy S. Lin, Charlie Y. Shi, Thy M. Pham, Namita Bisaria, Gina M. Kelley, David P. Bartel Science. Author manuscript; available in PMC 2020 Jun 20. Published in final edited form as: Science. 2019 Dec…

Doctoral Thesis Title: Optimizing scientific innovation by learning on knowledge graph dynamics Publications while at MIT: 1. Learning on knowledge graph dynamics provides an early warning of impactful research. Weis JW, Jacobson JM. Nat Biotechnol. 2021 May 17. doi: 10.1038/s41587-021-00907-6. Online ahead of print. PMID: 34002098 2. Machine Learning Identifies Chemical Characteristics That Promote Enzyme Catalysis Brian…

Doctoral Thesis Title: Engineering self-assembling living structures with mammalian synthetic biology Publications while at MIT: 1. Self-organizing multicellular structures designed using synthetic biology. Tordoff J, Weiss R.Nature. 2018 Jul;559(7713):184-185. doi: 10.1038/d41586-018-05564-5.PMID: 29988052 No abstract available. 2. Correction: 3D aggregation of cells in packed microgel media. Morley CD, Tordoff J, O’Bryan CS, Weiss R, Angelini TE.Soft Matter. 2020 Jul 22;16(28):6684. doi: 10.1039/d0sm90130j.PMID: 32639490