News & Events

Event

MIT Computational & Systems Biology PhD Program Webinar

Posted
November 14, 2023

The MIT Computational and Systems Biology Program will hold a webinar on Friday November 17, 2023 from 1:30-2:30 EST.

Please join us to learn about the program, how to apply, and ask any questions you might have.

We look forward to meeting you!

Event

2023 MIT Virtual Graduate Fair

Posted
October 30, 2023

The MIT CSB Program will be participating in the 2023 MIT Virtual Graduate Fair on November 15th from 12:00 -2:00 PM EST!

Register and join us to learn more about the program and receive answers to your questions about applying to the program!

We look forward to meeting you!

Event

CSB Thesis Defense

Posted
October 20, 2023

PhD Candidate: Michael Murphy

Research Advisors: Prof. Ernest Fraenkel, Prof. Stefanie Jegelka

Date:  Monday, Oct 23, 2023

Time: 11 AM-12 PM

Room: 68-180

Title: Machine Learning Methods for High Throughput Biological Data

Abstract: 

Machine learning is becoming a pivotal tool in the analysis of datasets generated from high-throughput biological omics experiments. However, omics data introduces distinctive algorithmic challenges that set it apart from other domains where machine learning is applied. These challenges encompass issues such as limited data availability, complex noise, ambiguities in representation, and the absence of definitive ground truth for validation. In this thesis, I present three examples of machine learning applications to different omics modalities in which I address these challenges. In my...

Event

CSB Thesis Defense

Posted
October 11, 2023

Ph.D. Candidate:   Mirae Parker

Lab: Prof. Gene-Wei Li

Date and Time: Thursday, October 19, 2023, 1:45-2:45 PM

Format: Hybrid 

Location:68-180

Title:  New Tools for Measuring and Analyzing Bacterial Gene-Expression Dynamics

Abstract: 

Messenger RNAs (mRNAs) are essential targets of gene regulation. The cell adapts and grows by changing its gene-expression profile, which it can achieve by manipulating the rates of mRNA initiation and decay and thus changing the relative abundances of transcripts. To understand the biological significance of these transcriptomic changes it is useful to observe how these changes correlate with emergent downstream behaviors and phenotypes. To manipulate and predict transcriptomic changes, it is also helpful to identify the sites of RNA regulation (transcription...